Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 14/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257377 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL30324481 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL25253606 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL25216272 | 0.88 | PIK3CD (0.35) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL25205848 | 0.88 | PIK3CD (0.35) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL19836869 | 0.87 | PIK3CD (0.54) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL25268109 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL25217856 | 0.84 | PIK3CD (0.41) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL28936659 | 0.82 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA | |
| SCHEMBL28936655 | 0.82 | PIK3CD (0.39) | PIK3CDPIK3R1PIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149944-A1 | COMPOUNDS AS PROTEIN KINASE INHIBITORS | Fochon Biosciences, Ltd. (CN) | 2023-03-22 | — | — | EP | disclosed |
| CN-115605481-A | Compounds as kinase inhibitors | 重庆复尚源创医药技术有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |