Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 19/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24127376 | 1.00 | MAP3K5 (0.47) | MAP3K5MAPK8MAPK10 | |
| SCHEMBL30133721 | 1.00 | MAP3K5 (0.47) | MAP3K5MAPK8MAPK10 | |
| SCHEMBL30595990 | 0.90 | MAP3K5 (0.49) | MAP3K5 | |
| SCHEMBL24127337 | 0.90 | MAP3K5 (0.49) | MAP3K5 | |
| SCHEMBL24127084 | 0.90 | MAP3K5 (0.49) | MAP3K5 | |
| SCHEMBL24127437 | 0.87 | MAP3K5 (0.44) | MAP3K5MAPK8MAPK10 | |
| SCHEMBL30389781 | 0.87 | MAP3K5 (0.44) | MAP3K5MAPK8MAPK10 | |
| SCHEMBL24127439 | 0.85 | PDCD1 (0.47) | MAP3K5 | |
| SCHEMBL25312939 | 0.85 | PDCD1 (0.47) | MAP3K5 | |
| SCHEMBL30389787 | 0.85 | PDCD1 (0.47) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4174066-A1 | IMMUNOSUPPRESSANT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-05-03 | — | — | EP | disclosed |
| CN-115605475-A | Immunosuppressant, preparation method and application thereof | 上海和誉生物医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |