Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30133994 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR2CL3MBTL1 | |
| SCHEMBL30134207 | 0.95 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR2CL3MBTL1 | |
| SCHEMBL23526975 | 0.86 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| SCHEMBL23526977 | 0.86 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| Hydrochloric Acid SCHEMBL31133921 | 0.85 | SLC6A4 (0.48) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| SCHEMBL23526868 | 0.84 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| SCHEMBL23564390 | 0.84 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| SCHEMBL23526870 | 0.84 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| Hydrochloric Acid SCHEMBL23527151 | 0.83 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A | |
| Hydrochloric Acid SCHEMBL30900969 | 0.83 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR2CKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380936-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BeiGene, Ltd. (KY) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023011456-A1 | PYRAZOLOPYRIDINONE COMPOUNDS | BEIGENE, LTD. (KY) | 2023-02-09 | — | — | WO | disclosed |