Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8177591 | 1.00 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11117017 | 0.82 | NOTUM (0.56) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL1196802 | 0.79 | KMT2A (0.58) | NOTUMALDH1A1KMT2AKDM4ENPSR1 | |
| SCHEMBL29757989 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL29958128 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL23466554 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL15059524 | 0.79 | NOTUM (0.42) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL16615357 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL3009848 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E | |
| SCHEMBL27673577 | 0.79 | NOTUM (0.53) | NOTUMF2ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283750-B | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-118812507-A | Pyridine-N-oxide compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116283908-A | N-aromatic methyl pyridone derivative and preparation method and application thereof | 合肥工业大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283750-A | Heterocyclic amide derivative and preparation method and application thereof | 成都泰和伟业生物科技有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2023002984-A1 | METHOD FOR PRODUCING IMIDAZOLE COMPOUND | 小野薬品工業株式会社 | 2023-01-26 | — | — | WO | disclosed |