Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 15/20 | 0.78 |
| ▸ | VEGFA | P15692 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425036 | 1.00 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL28426265 | 1.00 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL28425034 | 1.00 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL30136495 | 1.00 | EPAS1 (0.78) | EPAS1VEGFA | |
| SCHEMBL28425970 | 0.80 | VEGFA (0.53) | EPAS1VEGFA | |
| SCHEMBL30136471 | 0.80 | VEGFA (0.53) | EPAS1VEGFA | |
| SCHEMBL28425966 | 0.80 | VEGFA (0.53) | EPAS1VEGFA | |
| SCHEMBL28894238 | 0.80 | EPAS1 (0.49) | EPAS1VEGFA | |
| SCHEMBL30136475 | 0.80 | EPAS1 (0.49) | EPAS1VEGFA | |
| SCHEMBL28424427 | 0.80 | EPAS1 (0.63) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303053-B | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2023-01-17 | — | — | CN | claimed |
| CN-111303053-B | Cyclopenta [ d ] pyrimidine compound and pharmaceutically acceptable salt, solvate or prodrug thereof and application | 中国海洋大学 | 2023-01-17 | — | — | CN | disclosed |