Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 19/20 | 0.64 |
| ▸ | RPS6KA2 | Q15349 | 4/20 | 0.57 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.57 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1982725 | 0.90 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1982846 | 0.90 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1981787 | 0.90 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137580 | 0.87 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137612 | 0.87 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19278402 | 0.85 | RPS6KA3 (0.67) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252924 | 0.85 | RPS6KA3 (0.67) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL1990125 | 0.84 | RPS6KA3 (0.61) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL19252841 | 0.83 | RPS6KA3 (0.53) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL5389081 | 0.81 | RPS6KA3 (0.53) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025016350-A1 | THIO-GLUTARIMIDO ISOINDOLINONE DERIVATIVE, BIFUNCTIONAL PROTEIN DEGRADER CONTAINING SAME, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2025-01-23 | — | — | WO | claimed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | claimed |
| WO-2024245443-A1 | COMPOUND BASED ON OXOISOINDOLINYL SUBSTITUTED TETRAHYDRO-2-PYRIMIDONE, AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |
| WO-2024188209-A1 | NEW E3 UBIQUITIN LIGASE LIGAND, PROTEIN DEGRADATION AGENT AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-09-19 | — | — | WO | disclosed |
| CN-115611897-A | Compounds as RSK2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-01-17 | — | — | CN | disclosed |