Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 19/20 | 0.54 |
| ▸ | RPS6KA2 | Q15349 | 4/20 | 0.52 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.51 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30137592 | 0.90 | RPS6KA3 (0.52) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137601 | 0.89 | RPS6KA3 (0.54) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137564 | 0.85 | RPS6KA3 (0.57) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137577 | 0.85 | RPS6KA3 (0.64) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137572 | 0.85 | RPS6KA3 (0.52) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137593 | 0.84 | RPS6KA3 (0.55) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137566 | 0.84 | RPS6KA3 (0.56) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137578 | 0.83 | RPS6KA3 (0.58) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137625 | 0.83 | RPS6KA3 (0.55) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 | |
| SCHEMBL30137643 | 0.81 | RPS6KA3 (0.53) | RPS6KA3RPS6KA2RPS6KA1RPS6KA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611897-A | Compounds as RSK2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-01-17 | — | — | CN | disclosed |