Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.95 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.66 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30798398 | 1.00 | CRBN (0.95) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30139774 | 1.00 | CRBN (0.95) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL21946744 | 1.00 | CRBN (0.95) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL21946754 | 0.99 | CRBN (0.93) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL21946896 | 0.99 | CRBN (0.93) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL24926143 | 0.99 | CRBN (0.93) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30066311 | 0.99 | CRBN (0.93) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL21946755 | 0.99 | CRBN (0.93) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL25170816 | 0.97 | CRBN (1.00) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL30161018 | 0.93 | CRBN (0.86) | CRBNDDB1ALDH1A1CHRM2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022270994-A1 | NOVEL BIFUNCTIONAL HETEROCYCLIC COMPOUND HAVING BTK DEGRADATION FUNCTION VIA UBIQUITIN PROTEASOME PATHWAY, AND USE THEREOF | 한국화학연구원 | 2022-12-29 | — | — | WO | disclosed |