Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 10/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632636 | 0.83 | NOTUM (0.47) | NOTUMKEAP1P2RX7MAOAL3MBTL1 | |
| SCHEMBL75570 | 0.77 | NOTUM (0.63) | NOTUMKEAP1CYP19A1CYP2C9CYP3A4 | |
| SCHEMBL29084866 | 0.76 | NOTUM (0.61) | NOTUMKEAP1CYP19A1CYP2C9CYP3A4 | |
| SCHEMBL29379236 | 0.74 | NOTUM (0.47) | NOTUMKEAP1P2RX7MAOAL3MBTL1 | |
| Azobenzene SCHEMBL21956057 | 0.68 | NOTUM (0.52) | NOTUMKEAP1MAOACYP19A1ALDH1A1 | |
| SCHEMBL26156419 | 0.67 | NOTUM (0.60) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL10447781 | 0.64 | NOTUM (0.78) | NOTUMKEAP1CYP19A1 | |
| SCHEMBL342739 | 0.64 | NOTUM (1.00) | NOTUMALDH1A1MAPTHTT | |
| Tromethamine SCHEMBL17472522 | 0.64 | NOTUM (0.46) | NOTUMKEAP1MAOAL3MBTL1CYP19A1 | |
| SCHEMBL14961974 | 0.62 | NOTUM (0.75) | NOTUMKEAP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521244-A | Method for constructing carbon-sulfur/selenium bond through triazole compound and sulfur/selenide | 四川大学 | 2022-12-27 | — | — | CN | disclosed |