Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.65 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.51 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30126414 | 0.90 | EGFR (0.65) | EGFREPHA2KDREPHB4ERBB2 | |
| SCHEMBL28492086 | 0.85 | EGFR (0.65) | EGFREPHA2KDREPHB4ERBB2 | |
| SCHEMBL30640241 | 0.85 | EGFR (0.65) | EGFREPHA2KDREPHB4ERBB2 | |
| SCHEMBL30126169 | 0.82 | EGFR (0.65) | EGFR | |
| SCHEMBL21541680 | 0.82 | EGFR (0.65) | EGFR | |
| SCHEMBL13604777 | 0.82 | EGFR (0.69) | EGFRKDRKCNH2 | |
| SCHEMBL2700855 | 0.81 | EGFR (0.64) | EGFRERBB2 | |
| SCHEMBL29781316 | 0.81 | EGFR (0.64) | EGFRKDRERBB2 | |
| SCHEMBL28120253 | 0.81 | EGFR (0.64) | EGFREPHA2KDREPHB4ERBB2 | |
| SCHEMBL26449347 | 0.81 | EGFR (0.64) | EGFREPHA2KDREPHB4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |