Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140389 | 0.96 | EGFR (0.52) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140139 | 0.96 | EGFR (0.52) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140406 | 0.96 | EGFR (0.52) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140268 | 0.93 | EGFR (0.48) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140116 | 0.92 | EPHA2 (0.44) | EGFRGPR119ERBB2PIK3CDPIK3CA | |
| SCHEMBL30140114 | 0.91 | EGFR (0.42) | EGFRGPR119ERBB2PIK3CDPIK3CA | |
| SCHEMBL30140316 | 0.90 | EGFR (0.48) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140204 | 0.90 | EGFR (0.46) | EGFRGPR119ERBB2KCNH2PIK3CD | |
| SCHEMBL30140213 | 0.90 | EPHA2 (0.43) | EGFRGPR119ERBB2PIK3CDPIK3CA | |
| SCHEMBL30140188 | 0.90 | EPHA2 (0.43) | EGFRGPR119ERBB2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |