Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 15/20 | 0.49 |
| ▸ | KDR | P35968 | 6/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 6/20 | 0.49 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140321 | 0.86 | EGFR (0.46) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140203 | 0.86 | EGFR (0.45) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140140 | 0.86 | EGFR (0.45) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140065 | 0.85 | EPHA2 (0.41) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140177 | 0.85 | EPHA2 (0.41) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140390 | 0.83 | EPHA2 (0.41) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140209 | 0.83 | EPHA2 (0.41) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140098 | 0.83 | EPHA2 (0.41) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140096 | 0.83 | EGFR (0.49) | EPHA2KDREPHB4EGFRERBB2 | |
| SCHEMBL30140250 | 0.82 | EPHA2 (0.40) | EPHA2KDREPHB4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |