Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 1.00 |
| ▸ | ATRIP | Q8WXE1 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17501595 | 1.00 | ATR (1.00) | ATRATRIP | |
| SCHEMBL20482887 | 0.92 | ATR (0.84) | ATRATRIP | |
| SCHEMBL18109965 | 0.92 | ATR (1.00) | ATRATRIP | |
| SCHEMBL23837790 | 0.91 | ATR (0.84) | ATRATRIP | |
| SCHEMBL30140481 | 0.90 | ATR (0.86) | ATRATRIP | |
| SCHEMBL17501324 | 0.90 | ATR (0.86) | ATRATRIP | |
| SCHEMBL20081829 | 0.90 | ATR (0.82) | ATRATRIP | |
| SCHEMBL17501484 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL17501441 | 0.89 | ATR (1.00) | ATRATRIP | |
| SCHEMBL30140527 | 0.89 | ATR (1.00) | ATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11529356-B2 | 2-(morpholin-4-yl)-1,7-naphthyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11529356-B2 | 2-(morpholin-4-yl)-1,7-naphthyridines | POLQ, CCND2, NRAS | ATR 3508/4885ATRIP 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.