Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20541004 | 1.00 | KLKB1 (0.61) | KLKB1BTK | |
| SCHEMBL24105389 | 0.91 | KLKB1 (0.61) | KLKB1BTK | |
| SCHEMBL21746525 | 0.90 | KLKB1 (0.61) | KLKB1BTK | |
| SCHEMBL26310061 | 0.90 | KLKB1 (0.52) | KLKB1 | |
| SCHEMBL24105334 | 0.88 | KLKB1 (0.53) | KLKB1 | |
| SCHEMBL30140731 | 0.88 | KLKB1 (0.61) | KLKB1 | |
| SCHEMBL23769242 | 0.88 | BTK (0.49) | KLKB1BTK | |
| SCHEMBL20540770 | 0.88 | KLKB1 (0.57) | KLKB1BTK | |
| SCHEMBL31033231 | 0.88 | KLKB1 (0.57) | KLKB1BTK | |
| SCHEMBL23769217 | 0.87 | KLKB1 (0.49) | KLKB1BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-110546146-B | Heteroaryl carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2023-02-21 | — | — | CN | disclosed |