Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21713014 | 1.00 | KLKB1 (0.59) | KLKB1 | |
| SCHEMBL23769156 | 0.93 | KLKB1 (0.51) | KLKB1 | |
| SCHEMBL23769145 | 0.91 | KLKB1 (0.50) | KLKB1 | |
| SCHEMBL23769154 | 0.91 | KLKB1 (0.50) | KLKB1 | |
| SCHEMBL23768888 | 0.91 | KLKB1 (0.50) | KLKB1 | |
| SCHEMBL29906543 | 0.90 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL30087407 | 0.90 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL23754175 | 0.90 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL23754058 | 0.90 | KLKB1 (0.49) | KLKB1 | |
| SCHEMBL23769402 | 0.89 | KLKB1 (0.61) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039181-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-110546146-B | Heteroaryl carboxamide derivatives as plasma kallikrein inhibitors | 勃林格殷格翰国际有限公司 | 2023-02-21 | — | — | CN | disclosed |