Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | VIPR2 | P41587 | 5/20 | 0.47 |
| ▸ | VIPR1 | P32241 | 3/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.46 |
| ▸ | NPY1R | P25929 | 4/20 | 0.46 |
| ▸ | NPY4R | P50391 | 4/20 | 0.46 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809691 | 0.94 | NPY4R (0.51) | TFPIRXFP1NPY5RNPY1RNPY4R | |
| SCHEMBL30084577 | 0.93 | TFPI (0.48) | TFPIRXFP1KEAP1NPY5RNPY1R | |
| SCHEMBL29546204 | 0.92 | NPY4R (0.52) | TFPINPY5RNPY1RNPY4RNPY2R | |
| SCHEMBL29545125 | 0.92 | NPY4R (0.52) | TFPINPY5RNPY1RNPY4RNPY2R | |
| SCHEMBL31676593 | 0.92 | TFPI (0.45) | TFPIRXFP1NPY5RNPY1RNPY4R | |
| SCHEMBL31676591 | 0.92 | TFPI (0.45) | TFPIRXFP1NPY5RNPY1RNPY4R | |
| SCHEMBL30905693 | 0.91 | TFPI (0.54) | TFPIRXFP1KEAP1VIPR1NPY5R | |
| SCHEMBL30966641 | 0.91 | TFPI (0.49) | TFPIRXFP1KEAP1NPY5RNPY1R | |
| SCHEMBL30905699 | 0.91 | TFPI (0.53) | TFPIRXFP1KEAP1VIPR1NPY5R | |
| SCHEMBL28081230 | 0.90 | TFPI (0.54) | TFPIRXFP1KEAP1VIPR2VIPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230050804-A1 | USE OF CCDC157 GENE AND MUTANT GENES THEREOF AS MOLECULAR MARKERS IN DIAGNOSIS OF MALE INFERTILITY DISEASES | ZHEJIANG UNIVERSITY (CN) | 2023-02-16 | — | — | US | disclosed |