Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 17/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31066913 | 1.00 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL678438 | 1.00 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7502732 | 0.90 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7501078 | 0.86 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7493988 | 0.85 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7497088 | 0.84 | PDE5A (0.72) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7504986 | 0.84 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL7499068 | 0.84 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL31034788 | 0.83 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 | |
| SCHEMBL2458882 | 0.83 | PDE5A (1.00) | PDE5ACLK4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023149407-A1 | LUNG MESENCHYMAL CELLS AND METHOD FOR PRODUCING LUNG MESENCHYMAL CELLS | 国立大学法人京都大学 | 2023-08-10 | — | — | WO | disclosed |
| WO-2023286852-A1 | STRUCTURE AND USE THEREOF | 株式会社セルファイバ | 2023-01-19 | — | — | WO | disclosed |