Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906241 | 1.00 | SCN10A (0.42) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24758289 | 0.88 | SCN10A (0.45) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24906419 | 0.85 | SCN10A (0.45) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24906520 | 0.85 | SCN10A (0.43) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24906338 | 0.85 | SCN10A (0.43) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24906523 | 0.85 | SCN10A (0.43) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24757353 | 0.83 | SCN10A (0.48) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL24906501 | 0.83 | SCN10A (0.43) | SCN10ANR1I2CACNA1C | |
| SCHEMBL24757351 | 0.83 | CA1 (0.46) | SCN10ANR1I2CACNA1CCA12CA1 | |
| SCHEMBL30895634 | 0.82 | SCN10A (0.44) | SCN10ANR1I2CACNA1CCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | claimed |
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |