Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 15/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906351 | 1.00 | SCN10A (0.39) | SCN10AANO1GRM4OPRM1SLC10A1 | |
| SCHEMBL24906312 | 1.00 | SCN10A (0.39) | SCN10AANO1GRM4OPRM1SLC10A1 | |
| SCHEMBL24906535 | 0.94 | ANO1 (0.40) | SCN10AANO1OPRM1SLC10A1 | |
| SCHEMBL24906498 | 0.89 | SCN10A (0.42) | SCN10AANO1 | |
| SCHEMBL30141381 | 0.89 | SCN10A (0.43) | SCN10AANO1 | |
| SCHEMBL24757339 | 0.89 | SCN10A (0.43) | SCN10AANO1 | |
| SCHEMBL24906469 | 0.89 | SCN10A (0.43) | SCN10AANO1 | |
| SCHEMBL24906509 | 0.87 | SCN10A (0.42) | SCN10A | |
| SCHEMBL24757277 | 0.85 | ANO1 (0.44) | SCN10AANO1OPRM1 | |
| SCHEMBL30107043 | 0.85 | ANO1 (0.44) | SCN10AANO1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | claimed |
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |