⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195834 | 0.84 | HTT (0.31) | — | |
| SCHEMBL6850764 | 0.81 | — | — | |
| SCHEMBL2735688 | 0.77 | — | — | |
| SCHEMBL6872093 | 0.71 | — | — | |
| SCHEMBL20734528 | 0.71 | — | — | |
| SCHEMBL17963363 | 0.70 | — | — | |
| SCHEMBL25450634 | 0.70 | — | — | |
| SCHEMBL2528825 | 0.67 | — | — | |
| SCHEMBL1204756 | 0.67 | CA1 (0.32) | — | |
| SCHEMBL21720048 | 0.66 | CNR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | claimed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | claimed |