Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15348614 | 1.00 | SMYD2 (0.38) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL15348613 | 1.00 | SMYD2 (0.38) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL31048362 | 0.96 | SMYD2 (0.37) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL1149963 | 0.92 | SMYD2 (0.39) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL6237907 | 0.92 | SMYD2 (0.39) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL1293220 | 0.92 | SMYD2 (0.39) | SMYD2IRAK4CTSDPDCD1LG2CD274 | |
| SCHEMBL31122947 | 0.83 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL14285577 | 0.80 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9558690 | 0.80 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9558683 | 0.80 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268065-A1 | COMPOUNDS AS ERK INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2022-12-29 | — | — | WO | disclosed |