Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 12/20 | 0.33 |
| ▸ | RAF1 | P04049 | 4/20 | 0.31 |
| ▸ | BRAF | P15056 | 4/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976025 | 0.95 | ANO1 (0.42) | ANO1AKR1C3AKR1C2SCN10ARAF1 | |
| SCHEMBL24757786 | 0.89 | ANO1 (0.44) | ANO1AKR1C3AKR1C2SCN10A | |
| SCHEMBL24758438 | 0.87 | ANO1 (0.38) | ANO1AKR1C3AKR1C2SCN10A | |
| SCHEMBL24759021 | 0.87 | SCN10A (0.42) | ANO1SCN10A | |
| SCHEMBL24906478 | 0.86 | SCN10A (0.48) | SCN10A | |
| SCHEMBL30975765 | 0.85 | SCN10A (0.40) | ANO1SCN10A | |
| SCHEMBL30975848 | 0.85 | AKR1C3 (0.34) | ANO1AKR1C3AKR1C2SCN10ARAF1 | |
| SCHEMBL30976087 | 0.85 | AKR1C3 (0.35) | ANO1AKR1C3AKR1C2SCN10ANR3C1 | |
| SCHEMBL24757315 | 0.85 | AKR1C3 (0.35) | ANO1AKR1C3AKR1C2SCN10ANR3C1 | |
| SCHEMBL30975931 | 0.85 | SCN10A (0.34) | ANO1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4634159-A1 | SULFOXIMINES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | disclosed |
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |