Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 11/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24758320 | 1.00 | ANO1 (0.40) | ANO1MALT1SCN10AARAKR1C3 | |
| SCHEMBL30141341 | 0.93 | SCN10A (0.41) | ANO1SCN10AAKR1C3AKR1C2 | |
| SCHEMBL30141527 | 0.93 | SCN10A (0.42) | ANO1SCN10AAKR1C3AKR1C2RAF1 | |
| SCHEMBL24758318 | 0.93 | SCN10A (0.41) | ANO1SCN10AAKR1C3AKR1C2 | |
| SCHEMBL24758323 | 0.93 | SCN10A (0.42) | ANO1SCN10AAKR1C3AKR1C2RAF1 | |
| SCHEMBL24906226 | 0.88 | SCN10A (0.40) | ANO1SCN10AAKR1C3AKR1C2 | |
| SCHEMBL30141502 | 0.88 | SCN10A (0.40) | ANO1SCN10AAKR1C3AKR1C2 | |
| SCHEMBL24757846 | 0.88 | SCN10A (0.40) | ANO1SCN10AAKR1C3AKR1C2 | |
| SCHEMBL24906215 | 0.88 | SCN10A (0.42) | ANO1SCN10A | |
| SCHEMBL30141433 | 0.88 | SCN10A (0.42) | ANO1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355733-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022263498-A1 | SUBSTITUTED PYRAZOLE AMIDES | Grünenthal GmbH (DE) | 2022-12-22 | — | — | WO | disclosed |