Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23929885 | 0.84 | RET (0.51) | RET | |
| Hydrochloric Acid SCHEMBL29615025 | 0.83 | RET (0.50) | RET | |
| Hydrochloric Acid SCHEMBL30363115 | 0.83 | RET (0.50) | RET | |
| SCHEMBL31298400 | 0.80 | RET (0.42) | RET | |
| SCHEMBL29566683 | 0.79 | RET (0.45) | RET | |
| Hydrochloric Acid SCHEMBL28993707 | 0.78 | RET (0.44) | RET | |
| SCHEMBL30175335 | 0.77 | RET (0.37) | RET | |
| SCHEMBL30175294 | 0.77 | RET (0.43) | RET | |
| SCHEMBL25252185 | 0.77 | CDK2 (0.36) | RET | |
| SCHEMBL30175370 | 0.77 | CDK2 (0.36) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4136090-A1 | CRYSTALLINE RET INHIBITOR | Loxo Oncology, Inc. (US) | 2023-02-22 | — | — | EP | claimed |
| EP-4136090-A1 | CRYSTALLINE RET INHIBITOR | Loxo Oncology, Inc. (US) | 2023-02-22 | — | — | EP | disclosed |