Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 4/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.58 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.58 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.58 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24443754 | 0.82 | SMN1; SMN2 (0.37) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL660099 | 0.81 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL18426415 | 0.78 | GRIN1 (0.57) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL21518418 | 0.77 | EPHX2 (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL30444009 | 0.75 | KMT2A (0.47) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL30189438 | 0.74 | GRIN2D (0.49) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL292647 | 0.73 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL18426735 | 0.73 | GRIN2D (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL8061377 | 0.72 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL1072142 | 0.72 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4107198-B1 | POLYISOCYANATE PREPARATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2024-03-13 | — | — | EP | disclosed |
| EP-3560975-B2 | IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-12-06 | — | — | EP | disclosed |
| EP-3724251-B2 | IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3851472-B1 | IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-06-07 | — | — | EP | disclosed |
| EP-4107198-A1 | POLYISOCYANATE PREPARATIONS | Covestro Deutschland AG (DE) | 2022-12-28 | — | — | EP | disclosed |