Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 2/20 | 0.40 |
| ▸ | SKP1 | P63208 | 2/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16719386 | 1.00 | KIT (0.47) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL16755406 | 1.00 | KIT (0.47) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL17771848 | 0.91 | KIT (0.46) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL15390121 | 0.90 | KIT (0.46) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL16719642 | 0.90 | KIT (0.46) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL30571385 | 0.90 | KIT (0.46) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL16784356 | 0.89 | KIT (0.43) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL18950223 | 0.88 | KIT (0.48) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL19295448 | 0.88 | KIT (0.42) | KITMAP4K4CKS1BSKP1SKP2 | |
| SCHEMBL16616053 | 0.88 | KIT (0.47) | KITMAP4K4CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898210-B | Process for preparing pyrimidinylcyclopentane compounds | 豪夫迈·罗氏有限公司 | 2025-02-21 | — | — | CN | disclosed |
| CN-110590606-B | Process for preparing pyrimidylcyclopentane compounds | 豪夫迈·罗氏有限公司 | 2023-02-17 | — | — | CN | disclosed |