Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.64 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.64 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CCND1 | P24385 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CCNH | P51946 | 1/20 | 0.54 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072507 | 1.00 | CDK2 (0.64) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL5835764 | 0.89 | CDK2 (0.66) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL5835388 | 0.85 | CDK2 (0.67) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL6284013 | 0.83 | CDK2 (0.76) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL30142884 | 0.83 | NPC1 (0.59) | ALDH1A1SMN1; SMN2KDM4EPOLBMEN1 | |
| SCHEMBL5836180 | 0.83 | CDK2 (0.69) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL6177659 | 0.83 | CDK2 (0.73) | CDK2CCNE1CDK5ALDH1A1SMN1; SMN2 | |
| SCHEMBL24074020 | 0.83 | NPC1 (0.59) | ALDH1A1SMN1; SMN2KDM4EPOLBMEN1 | |
| SCHEMBL30142626 | 0.82 | KDR (0.65) | CDK2CCNE1CDK5KDM4EPOLB | |
| SCHEMBL24074022 | 0.82 | KDR (0.65) | CDK2CCNE1CDK5KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| CN-116472292-A | Modified proteins and protein degrading agents | 上海睿跃生物科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| EP-4157888-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | Cullgen (Shanghai), Inc. (CN) | 2023-04-05 | — | — | EP | disclosed |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | CDK2 500/4885CCNE1 696/4885CDK5 1532/4885 |
| US-20230057177-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | CDK2 500/4885CCNE1 696/4885CDK5 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.