Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | FES | P07332 | 1/20 | 0.74 |
| ▸ | RET | P07949 | 1/20 | 0.74 |
| ▸ | MARK3 | P27448 | 1/20 | 0.74 |
| ▸ | TYK2 | P29597 | 1/20 | 0.74 |
| ▸ | FLT4 | P35916 | 1/20 | 0.74 |
| ▸ | SYK | P43405 | 1/20 | 0.74 |
| ▸ | CLK2 | P49760 | 1/20 | 0.74 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30143012 | 0.89 | HTT (0.72) | HTTFESRETMARK3TYK2 | |
| SCHEMBL29800992 | 0.86 | HTT (1.00) | HTTSMN1; SMN2MMP13POLBKMT2A | |
| SCHEMBL1514550 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317181 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317211 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18334816 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317601 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317214 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317996 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 | |
| SCHEMBL18317546 | 0.86 | FLT4 (1.00) | FESRETMARK3TYK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |