Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.46 |
| ▸ | KLK7 | P49862 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23185762 | 1.00 | KMT2A (0.50) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL3830180 | 0.88 | KMT2A (0.60) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL3830184 | 0.88 | KMT2A (0.60) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL9430749 | 0.88 | KMT2A (0.60) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL31614132 | 0.84 | KMT2A (0.47) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL31200867 | 0.84 | KMT2A (0.47) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL31200587 | 0.84 | KMT2A (0.47) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL31529319 | 0.83 | KMT2A (0.48) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL25978594 | 0.83 | KMT2A (0.48) | KMT2AL3MBTL1KLK5KLK7PPARA | |
| SCHEMBL20488435 | 0.82 | EPHX2 (0.47) | KMT2AEPHX2CTSLCPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589618-B1 | PYRAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE IP NO 2 LTD (GB) | 2022-12-28 | — | — | EP | disclosed |