Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.64 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.64 |
| ▸ | LCK | P06239 | 4/20 | 0.63 |
| ▸ | LYN | P07948 | 1/20 | 0.63 |
| ▸ | SRC | P12931 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | TEK | Q02763 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | ITK | Q08881 | 2/20 | 0.54 |
| ▸ | TEC | P42680 | 1/20 | 0.52 |
| ▸ | TXK | P42681 | 1/20 | 0.52 |
| ▸ | BMX | P51813 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26098532 | 1.00 | BTK (0.64) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL24196915 | 0.96 | BTK (0.65) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL24196555 | 0.95 | BTK (0.67) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL22720709 | 0.94 | BTK (0.70) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25075259 | 0.93 | BTK (0.65) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL22720825 | 0.93 | BTK (0.66) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL30144775 | 0.93 | BTK (0.65) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25075181 | 0.93 | BTK (0.65) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25075054 | 0.93 | BTK (0.69) | BTKNUDT14NUDT5LCKLYN | |
| SCHEMBL25075465 | 0.92 | BTK (0.66) | BTKNUDT14NUDT5LCKLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023537-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE | ENDOTARGET INC. (US) | 2023-02-23 | — | — | WO | disclosed |