SCHEMBL30144690 — predicted protein targets

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	BTK	Q06187	20/20	0.78

▸	LCK	P06239	5/20	0.78

▸	LYN	P07948	4/20	0.78

▸	NUDT14	O95848	2/20	0.72

▸	NUDT5	Q9UKK9	2/20	0.72

▸	EGFR	P00533	6/20	0.72

▸	ITK	Q08881	4/20	0.72

▸	TEC	P42680	4/20	0.72

▸	BMX	P51813	4/20	0.72

▸	SRC	P12931	3/20	0.72

▸	ABL1	P00519	2/20	0.72

▸	ERBB2	P04626	2/20	0.72

▸	FYN	P06241	2/20	0.72

▸	YES1	P07947	2/20	0.72

▸	HCK	P08631	2/20	0.72

▸	FGR	P09769	2/20	0.72

▸	FER	P16591	2/20	0.72

▸	CSK	P41240	2/20	0.72

▸	BLK	P51451	2/20	0.72

▸	JAK3	P52333	2/20	0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25075213	1.00	BTK (0.78)	BTKLCKLYNNUDT14NUDT5
SCHEMBL30144783	0.91	BTK (0.72)	BTKLCKLYNNUDT14NUDT5
SCHEMBL25075212	0.91	BTK (0.72)	BTKLCKLYNNUDT14NUDT5
SCHEMBL22720793	0.89	BTK (0.75)	BTKLCKLYNNUDT14NUDT5
SCHEMBL22243244	0.89	BTK (0.82)	BTKLCKLYNNUDT14NUDT5
SCHEMBL22243281	0.89	BTK (0.82)	BTKLCKLYNNUDT14NUDT5
SCHEMBL7001715	0.89	BTK (0.82)	BTKLCKLYNNUDT14NUDT5
SCHEMBL29441896	0.89	BTK (0.82)	BTKLCKLYNNUDT14NUDT5
SCHEMBL15915382	0.88	BTK (0.84)	BTKLCKLYNNUDT14NUDT5
SCHEMBL2631407	0.88	BTK (0.84)	BTKLCKLYNNUDT14NUDT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023023537-A1	COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE	ENDOTARGET INC. (US)	2023-02-23	—	—	WO	disclosed