Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | FLT3 | P36888 | 6/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.63 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9517979 | 0.88 | PDGFRB (0.72) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL29368200 | 0.84 | FLT3 (0.67) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL216170 | 0.84 | FLT3 (0.67) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL28857183 | 0.83 | KDM4E (0.61) | ALOX15FLT3PDGFRBPDGFRAKMT2A | |
| SCHEMBL24113306 | 0.83 | FLT3 (0.68) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL30189510 | 0.83 | FLT3 (0.68) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL335655 | 0.83 | FLT3 (0.68) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL3883246 | 0.81 | FLT3 (0.67) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| SCHEMBL7877900 | 0.80 | FLT3 (0.54) | FLT3PDGFRBPDGFRAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7882033 | 0.79 | FLT3 (0.53) | FLT3PDGFRBPDGFRAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |