Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439839 | 1.00 | CNR2 (0.59) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL31026513 | 0.86 | CNR2 (0.60) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL2230620 | 0.86 | CNR2 (0.60) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL30980407 | 0.84 | CNR2 (0.59) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL4407862 | 0.82 | HRH4 (0.59) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL30052471 | 0.82 | HRH4 (0.59) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL4034426 | 0.81 | HRH4 (0.56) | CNR2HRH4DAOATAD2ALOX15 | |
| SCHEMBL6061270 | 0.81 | DAO (0.57) | CNR2PTPN11HRH4DAOATAD2 | |
| SCHEMBL1203267 | 0.80 | HRH4 (0.57) | CNR2HRH4DAOATAD2DRD3 | |
| SCHEMBL29414319 | 0.80 | HRH4 (0.57) | CNR2HRH4DAOATAD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |