Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 6/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21605020 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL30147314 | 0.89 | MALT1 (0.43) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL2297454 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL2298539 | 0.86 | POLB (0.54) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL21604981 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL21605000 | 0.85 | POLB (0.56) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL30147850 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL30147712 | 0.85 | POLB (0.56) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL21604777 | 0.84 | HPGD (0.58) | SMN1; SMN2MAPTPOLBKDM4ERAB9A | |
| SCHEMBL30147821 | 0.84 | HPGD (0.58) | SMN1; SMN2MAPTPOLBKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807266-B1 | PYRAZOLE DERIVATIVES AS MALT1 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-25 | — | — | EP | disclosed |
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |