Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MALT1 | Q9UDY8 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20265658 | 1.00 | POLB (0.61) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20265580 | 0.91 | MALT1 (0.66) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL30546555 | 0.91 | MALT1 (0.66) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20278285 | 0.89 | MALT1 (0.61) | MALT1 | |
| SCHEMBL5681145 | 0.83 | MALT1 (0.51) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20265599 | 0.83 | MALT1 (0.60) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20278379 | 0.83 | MALT1 (0.58) | MALT1 | |
| SCHEMBL20265845 | 0.83 | HPGD (0.54) | POLBMAPTMALT1 | |
| SCHEMBL20265406 | 0.83 | MALT1 (0.58) | POLBMAPTSMN1; SMN2MALT1 | |
| SCHEMBL20265336 | 0.83 | MALT1 (0.59) | POLBMAPTSMN1; SMN2MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112585128-B | Pyrazole derivatives as MALT1 inhibitors | 詹森药业有限公司 | 2023-02-21 | — | — | CN | disclosed |