SCHEMBL3014832

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL855689	0.89	BRAF (0.56)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL855798	0.89	BRAF (0.56)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL13271117	0.89	BRAF (0.56)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL30003614	0.89	BRAF (0.56)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL9930598	0.88	BRAF (0.55)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL412736	0.88	CYP2C9 (0.60)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL21152128	0.87	BRAF (0.54)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL3021554	0.85	BRAF (0.52)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL878744	0.82	BRAF (0.50)	BRAFCYP2C9CYP2C19CYP3A4RIPK2
	SCHEMBL12468027	0.80	CYP3A4 (0.60)	BRAFCYP2C9CYP2C19CYP3A4RIPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.