⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490005 | 0.97 | — | — | |
| Benzene SCHEMBL27796799 | 0.94 | AKR1C3 (0.43) | — | |
| SCHEMBL2083101 | 0.88 | ABAT (0.48) | — | |
| SCHEMBL2079668 | 0.88 | ABAT (0.48) | — | |
| SCHEMBL1839380 | 0.88 | MAPT (0.44) | — | |
| SCHEMBL6295811 | 0.79 | CYP2C19 (0.39) | — | |
| SCHEMBL29883233 | 0.78 | — | — | |
| SCHEMBL51838 | 0.78 | — | — | |
| SCHEMBL1666449 | 0.78 | — | — | |
| SCHEMBL3295484 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1532 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4735444-A1 | BENZYL (3-(METHYL(7H-PYRROLO[2,3-D]PYRIMIDIN-4YL)AMINO)CYCLOBUTYL) CARBAMATE OR A SALT THEREOF, METHOD FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE SYNTHESIS OF ABROCITINIB | Moehs Ibérica, S.L. (ES) | 2026-05-06 | — | — | EP | claimed |
| EP-4626886-A1 | JAK INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | OnQuality Pharmaceuticals China Ltd. (CN) | 2025-10-08 | — | — | EP | claimed |
| CN-119490397-A | Bicyclo [1.1.0] butanone compound and synthesis method thereof | 浙江工业大学 | 2025-02-21 | — | — | CN | claimed |
| CN-119462360-A | Synthesis method of 3-oxo-1-cyclobutanecarboxylic acid | 中昊(大连)化工研究设计院有限公司 | 2025-02-18 | — | — | CN | claimed |
| WO-2025003177-A1 | BENZYL (3-(METHYL(7H-PYRROLO[2,3-D]PYRIMIDIN-4YL)AMINO)CYCLOBUTYL) CARBAMATE OR A SALT THEREOF, METHOD FOR THE PREPARATION THEREOF, AND USE THEREOF IN THE SYNTHESIS OF ABROCITINIB | MOEHS IBERICA, S.L. (ES) | 2025-01-02 | — | — | WO | claimed |
| CN-118561689-B | Preparation method of 3-oxo-cyclobutanecarboxylic acid ester compound | 中节能万润股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118876522-A | Laminated bulletproof glass and preparation process thereof | 侯凯莉 | 2024-11-01 | — | — | CN | claimed |
| CN-118530108-B | Preparation method of 3-oxo-cyclobutanecarboxylic acid | 中节能万润股份有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-118561689-A | Preparation method of 3-oxo-cyclobutanecarboxylic acid ester compound | 中节能万润股份有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-118530108-A | Preparation method of 3-oxo-cyclobutanecarboxylic acid | 中节能万润股份有限公司 | 2024-08-23 | — | — | CN | claimed |
| CN-103232340-A | Synthesis method of 3-oxocyclobutanecarboxylic acid | LANZHOU WOJIN ENVIRONMENT PROT SCIENCE AND TECHNOLOGY CO LTD | 2013-08-07 | — | — | CN | claimed |
| CN-101555205-B | Preparing method of 3-oxo-1-cyclobutane-carboxylic acid | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2011-11-23 | — | — | CN | claimed |
| CN-101555205-A | Preparing method of 3-oxo-1-cyclobutane-carboxylic acid | ZHEJIANG GENEBEST PHARMACEUTIC (CN) | 2009-10-14 | — | — | CN | claimed |
| EP-1987036-A1 | HETERO-BYCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| WO-2007093520-A1 | HETERO-BYCYCLIC ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | claimed |
| US-20070191335-A1 | 4-{2-[5-(4,6-Dimethyl-pyrimidine-5-carbonyl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-ethyl}-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester,chemokine receptor antagonist; human immunodeficiency virus (HIV) infection, AIDS or ARC, antiinflammatory agent, autoimmune diseases, graft v. host disease | ROCHE PALO ALTO LLC | 2007-08-16 | — | — | US | claimed |
| CN-101001860-A | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (CH) | 2007-07-18 | — | — | CN | claimed |
| EP-1761542-A2 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-03-14 | — | — | EP | claimed |
| WO-2005121145-A2 | OCTAHYDRO-PYRROLO[3,4-C] DERIVATIVES AND THEIR USE AS ANTIVIRAL COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2005-12-22 | — | — | WO | claimed |