Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4932617 | 0.92 | KDM4E (0.58) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL29619308 | 0.92 | KDM4E (0.58) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5440917 | 0.92 | KDM4E (0.58) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5436539 | 0.90 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5444333 | 0.90 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5436833 | 0.90 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5444639 | 0.90 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL5438876 | 0.90 | KDM4E (0.57) | KDM4EMEN1RECQLKMT2ACA12 | |
| SCHEMBL9625496 | 0.86 | MEN1 (0.53) | KDM4EMEN1RECQLKMT2ACA12 | |
| Ethylenediamine SCHEMBL28949110 | 0.85 | KDM4E (0.53) | KDM4EMEN1RECQLKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536519-A | Preparation method of high-purity 2- (alpha-n-pentanone) benzoic acid and metal salt thereof | 吉林天衡药业有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-115536625-A | Preparation method of high-purity butylphthalide | 吉林天衡药业有限公司 | 2022-12-30 | — | — | CN | disclosed |