Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.84 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.84 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 9/20 | 0.55 |
| ▸ | TSHR | P16473 | 7/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30150607 | 1.00 | PTGER2 (0.84) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24818809 | 0.91 | PTGER2 (0.70) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL2432927 | 0.91 | PTGER2 (1.00) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24817251 | 0.90 | PTGER2 (0.80) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL30925661 | 0.89 | PTGER2 (0.81) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24817542 | 0.89 | PTGER4 (0.81) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24817294 | 0.89 | PTGER2 (0.81) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL2435176 | 0.88 | PTGER4 (0.80) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24817248 | 0.88 | PTGER2 (0.80) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 | |
| SCHEMBL24817250 | 0.88 | PTGER2 (0.80) | PTGER2PTGER4PTGDRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359399-A1 | EP2 ANTAGONIST COMPOUNDS | Reservoir Neuroscience, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272062-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |