Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900334 | 1.00 | KMT2A (0.58) | KMT2AEPHX2KDRHTR2AHTR2C | |
| SCHEMBL19900302 | 0.91 | KMT2A (0.58) | KMT2AEPHX2KDRHTR2AHTR2C | |
| SCHEMBL18038048 | 0.85 | EPHX2 (0.59) | KMT2AEPHX2IGF1RIDH1NPC1 | |
| SCHEMBL18038049 | 0.82 | KMT2A (0.67) | KMT2AEPHX2KDRIGF1RBRAF | |
| SCHEMBL18037981 | 0.82 | KMT2A (0.70) | KMT2AIDH1ALDH1A1NPC1GBA1 | |
| SCHEMBL18038020 | 0.79 | KMT2A (0.62) | KMT2AEPHX2IDH1TSHRALDH1A1 | |
| SCHEMBL30481107 | 0.78 | KDR (0.67) | KMT2AKDRTSHRALDH1A1TRPV1 | |
| SCHEMBL18053822 | 0.78 | KDR (0.67) | KMT2AKDRTSHRALDH1A1TRPV1 | |
| SCHEMBL30481106 | 0.78 | KDR (0.67) | KMT2AKDRTSHRALDH1A1TRPV1 | |
| SCHEMBL19900247 | 0.78 | MCHR1 (0.51) | EPHX2KDRHTR2CBRAFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115215807-A | Inhibition of OLIG2 activity | 科泰纳制药公司 | 2022-10-21 | — | — | CN | disclosed |