Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 20/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974969 | 1.00 | GLP1R (0.59) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL29574129 | 1.00 | GLP1R (0.59) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24330242 | 1.00 | GLP1R (0.59) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24265545 | 1.00 | GLP1R (0.59) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24338646 | 0.93 | GLP1R (0.60) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL30903419 | 0.93 | GLP1R (0.60) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL29241307 | 0.93 | GLP1R (0.60) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL30200239 | 0.93 | GLP1R (0.60) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24338435 | 0.91 | GLP1R (0.57) | GLP1RCYP2C8KCNH2HTR1AHTR2A | |
| SCHEMBL24330220 | 0.91 | GLP1R (0.64) | GLP1RCYP2C8KCNH2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362283-B | GLP-1 receptor agonists, compositions and uses thereof | 杭州中美华东制药有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022268152-A1 | GLP-1 RECEPTOR AGONIST AND COMPOSITION AND USE THEREOF | 杭州中美华东制药有限公司 | 2022-12-29 | — | — | WO | disclosed |