Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19718016 | 1.00 | TNKS2 (0.46) | TNKS2ERN1ALOX5AMY1APTGS2 | |
| SCHEMBL31482703 | 0.82 | ERN1 (0.51) | ERN1ALOX5AMY1APTGS2KDM4E | |
| SCHEMBL2171643 | 0.82 | ERN1 (0.51) | ERN1ALOX5AMY1APTGS2KDM4E | |
| SCHEMBL1619127 | 0.80 | TNKS2 (0.46) | TNKS2ALOX5PTGS2KDM4EMAPT | |
| SCHEMBL19828676 | 0.79 | TNKS2 (0.53) | TNKS2ERN1ALOX5PTGS2ALOX15 | |
| SCHEMBL19125408 | 0.75 | CYP4A11 (0.45) | TNKS2KDM4EMAPTHPGDALDH1A1 | |
| SCHEMBL22438980 | 0.75 | ERN1 (0.42) | ERN1ALOX5AMY1APTGS2KDM4E | |
| SCHEMBL30601513 | 0.75 | ERN1 (0.42) | ERN1ALOX5AMY1APTGS2KDM4E | |
| SCHEMBL31441189 | 0.75 | CYP4A11 (0.45) | KDM4EMAPTALDH1A1LMNAPOLB | |
| SCHEMBL5722870 | 0.75 | ERN1 (0.47) | ERN1ALOX5AMY1APTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |