Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21010919 | 0.85 | ESR1 (0.52) | ALOX5MEN1MAPTKMT2AKDM4E | |
| SCHEMBL10421264 | 0.80 | CA14 (0.44) | CYP3A4ALOX5MEN1MAPTKMT2A | |
| SCHEMBL21010916 | 0.76 | ESR1 (0.56) | CYP3A4ALOX5MEN1MAPTKMT2A | |
| SCHEMBL21010894 | 0.76 | ESR1 (0.56) | CYP3A4ALOX5MEN1MAPTKMT2A | |
| SCHEMBL21011165 | 0.74 | ESR2 (0.48) | CYP11B2CYP17A1CYP11B1CYP3A4CYP19A1 | |
| SCHEMBL12110844 | 0.74 | ESR1 (0.48) | CYP3A4ALOX5MEN1MAPTKMT2A | |
| SCHEMBL6335548 | 0.73 | CYP11B1 (0.47) | CYP11B2CYP17A1CYP11B1CYP3A4CYP19A1 | |
| SCHEMBL21010880 | 0.72 | ESR1 (0.56) | ALOX5MEN1MAPTKMT2AKDM4E | |
| SCHEMBL9128639 | 0.72 | ESR1 (0.70) | CYP11B2CYP17A1CYP11B1CYP3A4CYP19A1 | |
| SCHEMBL21010917 | 0.71 | ESR1 (0.54) | ALOX5MEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |