Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CBLB | Q13191 | 1/20 | 0.31 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818770 | 1.00 | S1PR1 (0.32) | S1PR1CBLBMAP3K5 | |
| SCHEMBL30153222 | 0.91 | CBLB (0.32) | CBLBMAP3K5 | |
| SCHEMBL30152903 | 0.91 | CBLB (0.32) | S1PR1CBLBMAP3K5 | |
| SCHEMBL24819058 | 0.91 | CBLB (0.32) | S1PR1CBLBMAP3K5 | |
| SCHEMBL24820810 | 0.91 | CBLB (0.32) | CBLBMAP3K5 | |
| SCHEMBL24820423 | 0.90 | CBLB (0.35) | CBLBMAP3K5 | |
| SCHEMBL30152756 | 0.90 | CBLB (0.35) | CBLBMAP3K5 | |
| SCHEMBL24820424 | 0.88 | CBLB (0.34) | CBLB | |
| SCHEMBL30153130 | 0.88 | CBLB (0.34) | CBLB | |
| SCHEMBL30152656 | 0.86 | CBLB (0.34) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. | 2025-05-22 | — | — | US | disclosed |
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163038-A1 | CBL-B MODULATORS AND USES THEREOF | CBLB, CBL, CBLC | S1PR1 3402/4885CBLB 1/4885MAP3K5 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.