Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24818610 | 1.00 | CBLB (0.33) | CBLBMAP3K5NSD2MYCNSD3 | |
| SCHEMBL30152929 | 0.92 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL30152681 | 0.92 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24820112 | 0.92 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24820581 | 0.92 | CBLB (0.33) | CBLBMAP3K5 | |
| SCHEMBL24821812 | 0.89 | CBLB (0.32) | CBLBMAP3K5 | |
| SCHEMBL30152793 | 0.89 | CBLB (0.32) | CBLBMAP3K5 | |
| SCHEMBL24821936 | 0.88 | CBLB (0.38) | CBLB | |
| SCHEMBL24820588 | 0.86 | CBLB (0.36) | CBLB | |
| SCHEMBL30152883 | 0.86 | CBLB (0.36) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-117858865-A | CBL-B modulators and uses thereof | 林伯士克莱奥公司 | 2024-04-09 | — | — | CN | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |