Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 2/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 7/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29190069 | 1.00 | CBLB (0.41) | CBLBTRPV3RAF1 | |
| SCHEMBL24819905 | 1.00 | CBLB (0.41) | CBLBTRPV3RAF1 | |
| SCHEMBL29190071 | 1.00 | CBLB (0.41) | CBLBTRPV3RAF1 | |
| SCHEMBL31579000 | 0.94 | CBLB (0.38) | CBLB | |
| SCHEMBL30153126 | 0.92 | CBLB (0.35) | CBLBTRPV3 | |
| SCHEMBL24820270 | 0.92 | CBLB (0.35) | CBLBTRPV3 | |
| SCHEMBL24819009 | 0.92 | CBLB (0.35) | CBLBTRPV3 | |
| SCHEMBL24820102 | 0.92 | CBLB (0.35) | CBLBRAF1 | |
| SCHEMBL30152688 | 0.92 | CBLB (0.35) | CBLBTRPV3 | |
| SCHEMBL30153020 | 0.92 | CBLB (0.35) | CBLBRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359381-A1 | CBL-B MODULATORS AND USES THEREOF | Nimbus Clio, Inc. (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022272248-A1 | CBL-B MODULATORS AND USES THEREOF | NIMBUS CLIO, INC. (US) | 2022-12-29 | — | — | WO | disclosed |