SCHEMBL30153671

SCHEMBL30153671

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 0.56
MDM4 O15151 3/20 0.54
TP53 P04637 3/20 0.54
CASP3 P42574 2/20 0.52
MDM2 Q00987 1/20 0.49
CTSK P43235 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990051 1.00 PTPN1 (0.56) PTPN1MDM4TP53CASP3MDM2
SCHEMBL29700028 1.00 PTPN1 (0.56) PTPN1MDM4TP53CASP3MDM2
SCHEMBL10630934 0.96 PTPN1 (0.53) PTPN1MDM4TP53CASP3MDM2
SCHEMBL15006479 0.96 PTPN1 (0.53) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL1002861 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL29714950 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL29376158 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL29351703 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL29385681 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2
N- (9-Fluorenylmethoxycarbonyl)-L-Leucine SCHEMBL120560 0.95 MDM4 (0.58) PTPN1MDM4TP53CASP3MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117024528-B Preparation method of Retatrutide 杭州信海医药科技有限公司 2024-03-22 CN claimed
CN-117024528-A Preparation method of Retatrutide 杭州信海医药科技有限公司 2023-11-10 CN claimed
CN-119823233-A Synthesis method of Ruitalutide and Ruitalutide 杭州思诺达医药科技有限责任公司 2025-04-15 CN disclosed
CN-119798119-A Industrial preparation method of single-protection amino acid 四川什邡市三高生化实业有限公司 2025-04-11 CN disclosed
CN-119708197-A Ruitalu Process for producing peptide 深圳翰宇药业股份有限公司 2025-03-28 CN disclosed
CN-117024528-B Preparation method of Retatrutide 杭州信海医药科技有限公司 2024-03-22 CN disclosed
CN-117024528-A Preparation method of Retatrutide 杭州信海医药科技有限公司 2023-11-10 CN disclosed
CN-113655131-B Fmoc-Ile-OH related substance detection method 吉尔多肽生物制药(大连市)有限公司 2023-09-29 CN disclosed
CN-116023467-A Solid-phase synthesis method of abamectin 江苏诺泰澳赛诺生物制药股份有限公司 2023-04-28 CN disclosed
CN-110563802-B Group of antibacterial peptide analogues containing N-methylated amino acid and N-terminal fatty acid modification, and synthetic method and application thereof 倪京满 2023-04-07 CN disclosed
CN-115541731-A Analysis method for protecting enantiomer of amino acid 南京锐志生物医药有限公司 2022-12-30 CN disclosed