SCHEMBL30154381

SCHEMBL30154381

CCOc1cc(N(CC)CC)ccc1C1(c2c(C)n(CC)c3ccccc23)OC(=O)c2nccnc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 5/20 0.35
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
TP53 P04637 5/20 0.33
THRB P10828 2/20 0.33
LMNA P02545 3/20 0.32
HTT P42858 1/20 0.32
HPGD P15428 1/20 0.32
POLB P06746 2/20 0.31
TSHR P16473 2/20 0.31
MAPT P10636 3/20 0.31
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3187828 1.00 SMN1; SMN2 (0.36) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53
SCHEMBL8024221 0.93 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53
SCHEMBL29735694 0.91 GSK3A (0.36) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53
SCHEMBL211485 0.91 GSK3A (0.36) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53
SCHEMBL30792926 0.91 CNR2 (0.40) ALDH1A1HTTMEN1KMT2A
SCHEMBL10594124 0.91 CNR2 (0.40) ALDH1A1HTTMEN1KMT2A
SCHEMBL3187819 0.91 CNR2 (0.40) ALDH1A1HTTMEN1KMT2A
SCHEMBL10595719 0.91 CNR2 (0.40) ALDH1A1HTTMEN1KMT2A
SCHEMBL10934926 0.90 GSK3A (0.33) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53
SCHEMBL30122739 0.89 SMN1; SMN2 (0.35) SMN1; SMN2ALDH1A1GSK3AGSK3BTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4373674-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PROVIDING A LITHOGRAPHIC PRINTING PLATE EASTMAN KODAK CO (US) 2025-09-03 EP disclosed
EP-4373674-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF USE Eastman Kodak Company (US) 2024-05-29 EP disclosed
CN-117677502-A Lithographic printing plate precursors and methods of use 伊斯曼柯达公司 2024-03-08 CN disclosed
WO-2023003712-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF USE EASTMAN KODAK COMPANY (US) 2023-01-26 WO disclosed