Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24027268 | 1.00 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL18606441 | 0.88 | LRRK2 (0.78) | LRRK2 | |
| SCHEMBL18606515 | 0.88 | LRRK2 (0.78) | LRRK2 | |
| SCHEMBL18634403 | 0.86 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL30154556 | 0.85 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24027219 | 0.85 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL18634601 | 0.83 | LRRK2 (0.80) | LRRK2 | |
| SCHEMBL18658828 | 0.83 | LRRK2 (0.80) | LRRK2 | |
| SCHEMBL20495535 | 0.82 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL30154551 | 0.82 | LRRK2 (1.00) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051304-B | Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2022-12-27 | — | — | CN | claimed |
| EP-3592741-B1 | NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-111051304-B | Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2022-12-27 | — | — | CN | disclosed |