Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20495517 | 1.00 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL18606364 | 0.87 | LRRK2 (0.78) | LRRK2 | |
| SCHEMBL30154532 | 0.84 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL24027269 | 0.84 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL25021732 | 0.84 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL18606497 | 0.83 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL18606254 | 0.83 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL18658754 | 0.83 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL18623688 | 0.83 | LRRK2 (0.75) | LRRK2 | |
| SCHEMBL18606419 | 0.83 | LRRK2 (0.71) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111051304-B | Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2022-12-27 | — | — | CN | claimed |
| EP-3592741-B1 | NOVEL IMIDAZO[4,5-C]QUINOLINE DERIVATIVES AS LRRK2 INHIBITORS | PFIZER (US) | 2023-02-15 | — | — | EP | disclosed |